Anjul Agarwal
anjul_g@rediffmail.com
International Journal of PharmTech Research
IJPTR
0974-4304
2455-9563
10.20902/2017
http://www.sphinxsai.com/pharmtech.php
2019
12
01
Securinega leucopyrus improves Memory and Learning in Alzheimer’s Model: An Experimental Study in Rat
J. Gopi
Chand
1
S. Amreen
Sultana
1
G. N. S. S. Chandra
Sekhar
1
D. Eswar
Tony
1
N. Rama
Lakshmi
1
A. Narendra
Babu
1
Rama Rao
Nadendla
1
Department of Pharmacology,
Chalapathi Institute of Pharmaceutical Sciences, Lam, Guntur, India
2019
01
07
120101
10.20902/IJPTR.2019.120101
http://dx.doi.org/10.20902/IJPTR.2019.120101
Alzheimer’s disease (AD) affects the central nervous system causing progressive
degeneration of neurons, which affect cognitive function of the individual. So, the aim of this
study was to identify the potential of aqueous and methanolic stem extracts of Securinega
leucopyrus to be used as a therapeutic agent against Alzheimer’s disease. The cognitive
impairment was produced by the methods, ethanol- induced cognitive impairment &diazepam
induced amnesia. The potentials of the extracts were determined by using Morris water maze
(MWM) test. Both the extracts showed significant learning and memory enhancement activity
http://sphinxsai.com/2019/ph_vol12_no1/1/(01-07)V12N1PT.pdf
Alzheimer’s disease
Securinega leucopyrus
Ethanol
diazepam
Morris water maze
https://www.alz.org/alzheimers_disease_what_is_alzheimers.asp
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