Anjul Agarwal
anjul_g@rediffmail.com
International Journal of PharmTech Research
IJPTR
0974-4304
2455-9563
10.20902/2017
http://www.sphinxsai.com/pharmtech.php
2018
11
4
A 4 year retrospective study of 141 cases of Non Hodgkin's Lymphoma in AL-Mouwasat University Hospital classified according to the 2008 WHO classification
Safaa
Qatleesho
1
Department of Pathology, Faculty of Medicine, Syrian Private University,
Damascus, Syria
2018
329
350
11405
10.20902/IJPTR.2018.11405
http://dx.doi.org/10.20902/IJPTR.2018.11405
The distribution of Non-Hodgkin lymphoma(NHL) subtypes varies in the
different geographical locations according to Word Health Organization(WHO)
classification and there is no accurate epidemiologic study of Non-Hodgkin
Lymphoma. The aim of the study was to: determine the different types of Non-Hodgkin
Lymphoma in all groups and finds its relation to sex and lymph node involvement and
analyze the anatomic distribution (nodal and extranodal) of NHL. This is a
retrospective descriptive study of 141 cases of nodal and extranodal NHL retrieved
from archives(cords) of all patients diagnosed with NHL at department of pathology of
AL-Mouwasat University Hospital during the period between 2013 and 2016. The
diagnosis was assessed with immunohstochemical results, categorized and reclassified
according to the WHO classification of lymphoid neoplasms( 2008 , 2016 inorder). Out
of 201 patients diagnosed with malignant lymphoma(ML),141 (70%) had NHL and 60 (30%)
had Hodgkin Lymphoma, out of 141 patient who had NHL a male predominance was observed
(92/141 ,65%). B-cell lymphoma were the most frequent type of NHL (119/141 ,84%).Diffuse
large B cell lymphoma(DLBCL) was the most common pattern o Total of 141 cases (42%)were
nodal and (58%)were extranodal. Cervical lymph nodes were the most common site s(29/59
,49%) followed by axillary These data are in agreement with those reported in Yemen and
Lebanon. The relative proportion of follicular in this study is much lesser than that reported in
Lebanon . The relative proportion of DLBCL in this study is much higher than that reported in
European and American , while proportion of CLL/SLL and plasma cell neoplasms is similar
http://www.sphinxsai.com/2018/ph_vol11_no4/1/(329-350)V11N04PT.pdf
NHL
WHO classification of lymphoid neoplasms
Jaffe, E. S. H. N., Stein, H., & Vardiman, J. W. (Eds.). World Health Organization Classification
ofTumours. Pathology and Genetics of Tumours of Haematopoietic and LymphoidTissues. Lyon,France:
IARC Press. 2001
Blood
Laurini, J. A., Perry, A. M., Boilesen, E., Diebold, J., MacLennan, K. A., Muller-Hermelink, H. K., &
Weisenburger, D. D.
120
24
4795
2012
10.1182/blood-2012-07-440073
Annals of Oncology
Anderson, J. R., Armitage, J. O., & Weisenburger, D. D.
9
7
717
1998
10.1023/A:1008265532487
Journal
of the National Cancer Institute
Eltom, M. A., Jemal, A., Mbulaiteye, S. M., Devesa, S. S., & Biggar, R. J.
94
16
1204
2002
10.1093/jnci/94.16.1204
Asian Pacific Journal of Cancer Prevention
Hanif, M., Zaidi, P., Kamal, S., & Hameed, A.
10
227
2009
Juan Rosai, M. D. Rosai and Ackerman’s Surgical pathology, 10thEdition.Mosby(USA):Elsevier; (2011)
Blood
Swerdlow, S. H., Campo, E., Pileri, S. A., Harris, N. L., Stein, H., Siebert, R., & Jaffe, E. S.
127
20
2375
2016
10.1182/blood-2016-01-643569
. CA: a Cancer Journal for Clinicians
Skarin, A. T., & Dorfman, D. M.
47
6
351
1997
10.3322/canjclin.47.6.351
Bangladesh Medical Journal
Akhter, A., Rahman, M. R., Majid, N., Shermin, S., Saleheen, M. S., & Rajib, R. C.
41
1
32
2012
CA: a Cancer Journal for Clinicians
Armitage, J. O.
55
6
368
2005
10.3322/canjclin.55.6.368
Journal of Current Medical Research and Practice
Humam, M. A. A., Al-Nakhbi, N. A., Melkat, A. A., Almontaser, T. M., & Binnabhan, A. S.
1
2
6
2016
10.4103/2357-0121.192538
Journal of Cancer Research and Therapeutics
Mondal, S. K., Mandal, P. K., Roy, S. D., Chattopadhyay, S., Roy, S., & Biswas, P. K.
10
2
354
2014
10.4103/0973-1482.136639
APJCP
Claude Sader-Ghorra, Samah Naderi, Joseph Kattan
15
5825
2014
American Journal of Hematology
Yoon, S. O., Suh, C., Lee, D. H., Chi, H.-S., Park, C. J., Jang, S.-S., & Huh, J.
85
10
760
2010
10.1002/ajh.21824
European Journal of Clinical Nutrition
Leo, Q. J. N., Ollberding, N. J., Wilkens, L. R., Kolonel, L. N., Henderson, B. E., Le Marchand, L., &
Maskarinec, G.
70
1
41
2016
10.1038/ejcn.2015.139
CA: a Cancer Journal for
Clinicians
Teras, L.R., DeSantis, C.E., Cerhan, J.R., Morton, L.M., Jemal, A., & Flowers, C.R.
66
6
443
2016
10.3322/caac.21357
Cancer Research
Devesa, S. S., & Fear, T.
52
5432
1992